Research progress of MR nanoprobers in targeting oral squamous cell carcinoma
10.13929/j.1672-8475.201810005
- Author:
Lipeng LIN
1
Author Information
1. School of Medical Imaging, Xuzhou Medical University
- Publication Type:Journal Article
- Keywords:
Carcinoma, squamous cell;
Magnetic resonance imaging;
Mouth;
Nanoprobe;
Non-invasive;
Targeted tracer
- From:
Chinese Journal of Interventional Imaging and Therapy
2019;16(6):364-367
- CountryChina
- Language:Chinese
-
Abstract:
For analyzing the migration ability of oral squamous cell carcinoma (OSCC) cells in vivo, invasive methods were often used in the past. The experimental animals would be executed within a certain period of time after cell transplantation, and the oral and maxillofacial tissues should be analyzed with pathological section. These method can not be used to observe the migration and proliferation of OSCC cells dynamically in the same experimental animal in vivo. With the development of non-invasive methods in recent years, the highly specific protein expressed in OSCC cells can be labeled with MR technology using nanoparticles as contrast agent, thus to target and trace the metastasis in vivo, and to speculate the specific stages of OSCC. The advancements of targeting and tracing OSCC with MR nanomolecular probes were reviewed in this article.
