Evaluation of left ventricular systolic function in children with left ventricular noncompaction using real-time three-dimensional echocardiography
10.13929/j.1672-8475.201811010
- Author:
Xinyang LI
1
Author Information
1. Department of Ultrasound, Shengjing Hospital of China Medical University
- Publication Type:Journal Article
- Keywords:
Echocardiography;
;
left;
Myocardial noncompaction;
Real-time;
three-dimensional;
Ventricular function
- From:
Chinese Journal of Interventional Imaging and Therapy
2019;16(8):475-480
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the value of real-time three-dimensional echocardiography (RT-3DE) for evaluating left ventricular global and regional systolic function in children with left ventricular noncompaction (LVNC). Methods: According to left ventricular ejection fraction (LVEF) detected with conventional echocardiography, 34 children with LVNC were divided into LVEF normal group (group A, LVEF≥50%, n=25) and LVEF reduced group (group B, LVEF<50%, n=9), while 20 healthy children were selected as normal control group (group C) at the same period. RT-3DE examinations were performed, left ventricular end-systolic volume (LVESV), left ventricular end-diastolic volume (LVEDV) and LVEF were measured. The ratio of noncompaction myocardium to compaction myocardium (NC/C) at the thickest area on end-systolic count were calculated. The involvements of left ventricular 17-segment myocardium were observed. Regional end-diastolic volume (rEDV), regional end-systolic volume (rESV) and regional ejection fraction (rEF) were obtained with left ventricular volume-time curve analysis. The data were statistically analyzed. Results: There was no statistical difference of LVEDV (t=-0.17, P=0.87), LVESV (t=0.79, P=0.44) and LVEF (t=-1.72, P=0.10) between group A and C, nor of LVEDV (t=1.62, P=0.15) between group B and C. In group B, LVESV significantly increased (t=2.85, P=0.03), while LVEF significantly decreased compared with that in group C (t=-6.15, P<0.01). No statistical difference of NC/C was found between group A and B (t=-1.15, P=0.27), but the number of affected segments in group A was significantly fewer than that in group B (t=-4.59, P=0.03). There was no statistical difference of rEDV and rESV in all of 17 segments of myocardium in left ventricular between group A and C (all P>0.05), while rEF of apical septal, inferior and lateral segments, as well as med inferoseptal, inferior and inferolateral segments were significantly different between group A and C (all P<0.05). There was no significant difference of rEDV in all 17 segments of myocardium in left ventricular between group B and C (all P>0.05), while rESV of basal inferolateral and anterolateral segments, med anterior, anteroseptal, inferior, inferolateral and anterolateral segments, apical anterior, septal and lateral segments, as well as rEF in all 17 segments of myocardium in left ventricular were significantly different between group B and C (all P<0.05). Conclusion: RT-3DE can be used to evaluate the regional and global systolic function, which is helpful to early diagnosis, treatment and prognosis of LVNC children.
