Diffusion kurtosis imaging in evaluating changes of brain parenchyma microstructure in hypertensive patients with normal blood pressure control
10.13929/j.issn.1672-8475.2020.04.008
- Author:
Weixin WANG
1
Author Information
1. Department of Radiology, Dongfang Hospital of Beijing University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Cerebral microstructure;
Diffusion kurtorsis imaging;
Hypertension;
Magnetic resonance imaging
- From:
Chinese Journal of Interventional Imaging and Therapy
2020;17(4):224-227
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the application value of diffusion kurtosis imaging (DKI) for evaluating brain parenchyma microstructures changes in hypertensive patients with normal blood pressure control. Methods: Totally 22 patients with primary hypertension with blood pressure controlled in normal range were enrolled in observation group, while 19 healthy volunteers were selected as control group. DKI was performed in all subjects, and the mean kurtosis (MK), kurtosis anisotropy (KA), axial kurtosis (AK) and radial kurtosis (RK) of each brain area were measured and compared between the two groups. Results: MK values in right frontal lobe, right inner capsule knee and right cerebellum of observation group were lower than that of control group, whereas in right parietal lobe was higher than in control group(all P<0.05). The pontine KA value in observation group was lower than that in control group (P<0.05). AK values of left parietal lobe and right pallidum of observation group were lower than that in control group, of left red nucleus, right cerebellum and pontine were higher than that in control group (all P<0.05). The values of RK in right inner capsule knee, right cerebellum and left occipital lobe in observation group were lower than that in control group, and of right putamen was higher than that in control group (all P<0.05). Conclusion: DKI can be used to monitor changes of brain parenchyma microstructures in hypertensive patients with normal blood pressure control.
