Research progress of drug-coated balloon therapy for lower extremity atherosclerotic disease
10.13929/j.issn.1672-8475.2020.09.012
- VernacularTitle: 药物涂层球囊治疗下肢动脉疾病研究进展
- Author:
Yang ZHANG
1
Author Information
1. Department of Interventional Radiology and Vascular Surgery, Peking University First Hospital
- Publication Type:Journal Article
- Keywords:
Angioplasty, balloon;
Arterial occlusive diseases;
Arteriosclerosis;
Peripheral arterial disease
- From:
Chinese Journal of Interventional Imaging and Therapy
2020;17(9):565-568
- CountryChina
- Language:Chinese
-
Abstract:
Lower extremity artery disease (LEAD) is a kind of disease caused by atherosclerosis, which leads to narrowing and occlusion of lower extremity artery and causes ischemia symptoms of corresponding limbs. Endovascular intervention has become the main treatment method for LEAD, mainly including percutaneous transluminal angioplasty (PTA) and stent implantation, but high restenosis rate is still unavoidable after treatment. Drug-coated balloon (DCB) can inhibit intimal hyperplasia and inflammation while avoid the retention of foreign bodies, having good therapeutic effects on both primary lesions and in-stent restenosis. The principle of DCB therapy, application status and research advancements of DCB for LEAD were reviewed in this article.