Role of KIAA1199 Gene in Digestive System Neoplasms
10.3969/j.issn.1008-7125.2019.01.012
- Author:
Qingqing DONG
1
Author Information
1. Department of Gastroenterology, Shanghai Ninth People's Hospital, Shanghai JiaoTong University School of Medicine
- Publication Type:Journal Article
- Keywords:
Cell Migration;
Cell Proliferation;
Digestive System Neoplasms;
KIAA1199 Gene
- From:
Chinese Journal of Gastroenterology
2019;24(1):51-53
- CountryChina
- Language:Chinese
-
Abstract:
KIAA1199 gene is an important member of the HUGE database, and is involved in the transduction of intracellular signaling pathway through epigenetic mechanism, regulating the cell growth, differentiation, apoptosis and migration. Recent studies showed that KIAA1199 gene is closely related to tumorigenesis and tumor development. The expression of KIAA1199 gene is highly upregulated in many types of tumor, especially in digestive system neoplasms, and having the effects of promoting proliferation, adhesion, invasion and migration of tumor cells. This article reviewed the role of KIAA1199 gene in digestive system neoplasms.
