Clinicopathological Analysis of Gastric Mucosal Biopsy of 12 Cases With Rare Diseases
10.3969/j.issn.1008-7125.2019.02.009
- Author:
Yuyan LIU
1
Author Information
1. Department of Pathology, The First Hospital of Harbin
- Publication Type:Journal Article
- Keywords:
Biopsy;
Cytomegalovirus Infections;
Immunohistochemistry;
Neoplasms Metastasis;
Rare Diseases;
Stomach
- From:
Chinese Journal of Gastroenterology
2019;24(2):103-106
- CountryChina
- Language:Chinese
-
Abstract:
Background: The clinical manifestations of some rare diseases of the stomach are nonspecific, which may lead to missed diagnosis, misdiagnosis, and delayed or inappropriate management. Aims: To investigate the clinicopathological features and immunohistochemistry of some rare diseases of the stomach and their application in diagnosis and differential diagnosis. Methods: Gastroscopic biopsy specimens from Jan. 2017 to Dec. 2017 at the First Hospital of Harbin were reviewed. Twelve pathology-proved rare and easily misdiagnosed cases were screened out for analysis of clinicopathological features and immunohistochemical markers retrospectively. Results: Twelve rare diseases of the stomach, including one case of primary squamous cell carcinoma, 8 cases of metastatic carcinoma, two cases of primary neuroendocrine tumor, and one case of cytomegalovirus (CMV) infection were enrolled. In 8 cases of metastatic carcinoma, 2 were mammary origin, 3 were kidney origin, 2 were lung origin and 1 was liver origin. Each lesion had its unique histomorphological appearance and specific immunohistochemical markers. Conclusions: Tissue obtained from gastroscopic biopsy is limited. Familiar with the histomorphology and immunohistochemical markers of rare diseases of the stomach may avoid misdiagnosis and inappropriate management.
