Progress in Study on Ion Channel and Pathogenesis of Irritable Bowel Syndrome
10.3969/j.issn.1008-7125.2019.08.012
- VernacularTitle: 离子通道与肠易激综合征发病机制的研究进展
- Author:
Zihan GUO
1
Author Information
1. School of Basic Medical Sciences, Shandong First Medical University (Shandong Academy of Medical Sciences)
- Publication Type:Journal Article
- Keywords:
Calcium Channels;
Ion Channels;
Irritable Bowel Syndrome;
Pathogenesis;
Potassium Channels;
Sodium Channels
- From:
Chinese Journal of Gastroenterology
2019;24(8):501-504
- CountryChina
- Language:Chinese
-
Abstract:
Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder, mainly manifested as recurrent abdominal pain, abdominal discomfort and/or changes of defecation habits and stool character, its pathogenesis has not been fully clarified. The pathophysiology is characterized by visceral hypersensitivity, abnormal intestinal motility, and so on. Abnormality of ion channels may be in involved in the pathophysiological mechanism of IBS. This article reviewed the progress in study on ion channels and pathogenesis of IBS.