Relationship Between IL-33/ST2 Signal Pathway and Inflammatory Bowel Disease
10.3969/j.issn.1008-7125.2019.08.011
- VernacularTitle: IL-33/ST2信号通路与炎症性肠病的关系
- Author:
Yuemei DONG
1
Author Information
1. Department of Gastroenterology, The Second Affiliated Hospital of Zhengzhou University
- Publication Type:Journal Article
- Keywords:
Inflammatory Bowel Disease;
Interleukin-33;
ST2
- From:
Chinese Journal of Gastroenterology
2019;24(8):497-500
- CountryChina
- Language:Chinese
-
Abstract:
Interleukin-33 (IL-33), a novel identified member of IL-1 superfamily, is involved in the development and progress of various immune-related diseases, including inflammatory bowel disease (IBD), via its receptor ST2-mediated pathway, but the mechanism is not fully clarified. It has been reported that IL-33 plays a dual role in promoting inflammation and inducing protective effect in intestinal mucosa. This article reviewed the relationship between IL-33/ST2 signal pathway and IBD.
