Changes of Uric Acid Metabolism and its Potential Significance in Patients With Crohn's Disease
10.3969/j.issn.1008-7125.2019.09.008
- VernacularTitle: 克罗恩病患者尿酸代谢变化及其潜在意义
- Author:
Yuefeng GUO
1
Author Information
1. Department of Gastroenterology, the First Affiliated Hospital, Fujian Medical University, Institute of Digestive Diseases of Fujian Medical University
- Publication Type:Journal Article
- Keywords:
Crohn Disease;
Inflammatory Bowel Disease;
Metabolism;
Uric Acid
- From:
Chinese Journal of Gastroenterology
2019;24(9):557-560
- CountryChina
- Language:Chinese
-
Abstract:
In healthy subjects, about 2/3 serum uric acid (UA) was excreted by kidney, and 1/3 by intestine. UA not only has antioxidant effect, yet also promotes oxidation. Crohn's disease (CD), one of the non-specific gastrointestinal inflammatory diseases, is often associated with extraintestinal manifestations and systemic metabolic changes. Abnormal UA metabolism is commonly seen in CD patients, and its significance is not clarified, which brings trouble to clinical treatment. This article reviewed the changes of UA metabolism and its potential significance in patients with CD.
