Advances in Research on Serological Assessment of Portal Hypertension
10.3969/j.issn.1008-7125.2019.10.012
- Author:
Chenyan ZUO
1
Author Information
1. Department of Gastroenterology, First Affiliated Hospital of Nanjing Medical University
- Publication Type:Journal Article
- Keywords:
Hepatic Venous Pressure Gradient;
Noninvasive Assessment;
Portal Hypertension;
Serology
- From:
Chinese Journal of Gastroenterology
2019;24(10):631-634
- CountryChina
- Language:Chinese
-
Abstract:
Portal hypertension (PH) is a commonly seen complication of chronic liver disease and is a direct cause of decompensated cirrhosis. Early diagnosis of PH is essential for the treatment and prognosis of liver cirrhosis. Hepatic venous pressure gradient (HVPG) is the gold standard for the diagnosis of PH, but its invasiveness limits its use. At present, progress has been achieved on the noninvasive diagnostic techniques and of which the serological indicators are simple for use, including inflammatory mediators, vasoactive substances, extracellular matrix (ECM) components and their circulating degrading products. This article reviewed the advances in research on serological assessment of PH.
