Efficacy of Endoscopic Treatment in Patients With Colorectal Laterally Spreading Tumors
10.3969/j.issn.1008-7125.2020.03.007
- VernacularTitle: 内镜治疗结直肠侧向发育型肿瘤疗效观察
- Author:
Yongkang CUI
1
Author Information
1. Department of Gastroenterology, Baoshan Hospital of Integrated Traditional Chinese and Western Medicine
- Publication Type:Journal Article
- Keywords:
Colorectal Neoplasms;
Endoscopic Mucosal Resection;
Endoscopic Submucosal Dissection;
Laterally Spreading Tumors
- From:
Chinese Journal of Gastroenterology
2020;25(3):167-170
- CountryChina
- Language:Chinese
-
Abstract:
Background: Laterally spreading tumor (LST) is one of the commonly seen neoplastic lesions under colonoscopy. The risk of malignant transformation is considerably high. Aims: To compare the efficacy and safety of endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) for treatment of colorectal LST. Methods: Eighty-eight patients with colorectal LST were randomly divided into two groups and received EMR and ESD treatment, respectively, from Oct. 2016 to Dec. 2018 at the Baoshan Hospital of Integrated Traditional Chinese and Western Medicine. For LST larger than 20 mm in diameter in EMR group, piecemeal EMR was recommended. The procedure time, complications, en bloc resection rate and recurrence rate during 1-year follow-up were compared between the two groups. Results: All patients enrolled in this study achieved a complete resection. The procedure time of EMR was shorter than that of ESD [(23.73±6.19) min vs.(65.13±13.76) min], and the en bloc resection rate was higher (97.7% vs. 59.1%) and the recurrence rate was lower (11.4% vs. 31.8%) in ESD group than in EMR group (P<0.05). There were no significant differences in perforation and post-procedure bleeding rates between the two groups (P>0.05). In EMR group, the majority of recurrence occurred in cases with LST larger than 20 mm in diameter. Conclusions: For colorectal LST, the method of endoscopic treatment should be selected based on patients' clinical condition. Although the procedure time of EMR is shorter, ESD is more suitable for lesions larger than 20 mm in diameter.
