Comparative Study on Two Scoring Methods in Screening Early Gastric Cancer and Precancerous Lesion
10.3969/j.issn.1008-7125.2020.04.003
- VernacularTitle: 两种评分方法在早期胃癌和癌前病变筛查中的比较研究
- Author:
Wei GAO
1
Author Information
1. Department of Gastroenterology, School of Medicine, Shanghai Jiao Tong University
- Publication Type:Journal Article
- Keywords:
Diagnosis;
Japanese Gastric Cancer Screening Score;
New Gastric Cancer Screening Score;
Precancerous Lesions;
Stomach Neoplasms
- From:
Chinese Journal of Gastroenterology
2020;25(4):204-207
- CountryChina
- Language:Chinese
-
Abstract:
Background: The poor prognosis of gastric cancer is mainly attributed to the middle-late stages when diagnosed. Therefore, early screening is essential for reducing the mortality of gastric cancer. Aims: To compare the role of Japanese gastric cancer screening score and new gastric cancer screening score in detecting early gastric cancer and precancerous lesion. Methods: Healthy residents from Jan. 2016 to Dec. 2018 at a Shanghai community were enrolled. All subjects had gastroscopy performed, Japanese gastric cancer screening score and new gastric cancer screening score were evaluated. ROC curve was used to evaluate the value of the two scoring methods in detecting gastric cancer and precancerous lesion. Results: A total of 292 subjects were enrolled, of them 2 (0.7%) gastric cancer and 9 (3.1%) precancerous lesion were detected. According to the Japanese gastric cancer screening score, 263 (90.1%) were in low-risk group, 27 (9.2%) in middle-risk group, and 2 (0.7%) in high-risk group. According to the new gastric cancer screening score, 214 (73.3%) were in low-risk group, 75 (25.7%) in middle-risk group, and 3 (1.0%) in high-risk group. The detection rate of gastric cancer and precancerous lesion in the high-risk and middle-risk groups by the Japanese gastric cancer screening score (17.2% vs. 2.3%, P=0.000) and the new gastric cancer screening score (10.3% vs. 1.4%, P=0.000) was significantly higher than that in the low-risk group. The two scoring methods were moderately consistent (κ=0.561, P=0.011). The sensitivities of two scoring methods for detecting gastric cancer and precancerous lesion were 0.455, 0.727, respectively, and the specificities were 0.915, 0.751, respectively. Conclusions: The two gastric cancer screening scoring methods have moderate consistency. The new gastric cancer screening score has a high value for the screening of gastric cancer and precancerous lesion, the detection rate of gastric cancer and precancerous lesion in high-risk and middle-risk groups is significantly higher than that in low-risk group.
