Multidisciplinary diagnosis and treatment of a child with hepatoblastoma and suspected coronavirus disease
10.3969/j.issn.1000-8179.2020.08.268
- VernacularTitle: COVID-19 疑似病例合并肝母细胞瘤多学科临床讨论
- Author:
Yumei MI
1
Author Information
1. Division of Infectious Disease, Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health
- Publication Type:Journal Article
- Keywords:
Corona virus disease 2019(COVID-19);
Diagnosis;
Hepatoblastoma (HB);
Management;
Multidisciplinary team (MDT);
Treatment
- From:
Chinese Journal of Clinical Oncology
2020;47(8):407-410
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To discuss the diagnosis, treatment, and multidisciplinary management of a child with hepatoblastoma (HB) and suspected coronavirus disease (COVID-19). Methods: A child with HB and suspected COVID-19 was admitted to the Children's Hospital, Zhejiang University School of Medicine, in February 2020. The diagnosis and treatment plan were discussed by a multidisciplinary team (MDT). After the MDT discussion, necessary examinations and tests were performed, including routine blood tests, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ribonucleic acid (RNA) and antibody tests, tumor marker tests, chest and abdomen computed tomography (CT), and an ultrasound. The administered treatment included the cisplatin+5-fluorouracil+vincristine (C5V) regimen and cefotaxime. Results: The patient was diagnosed as low-risk HB and completed the first stage of HB chemotherapy after the diagnosis of COVID-19 was ruled out. After 1 week in the hospital, the patient's body temperature returned to normal, the disposition and appetite improved, and all indexes reached the discharge standard. After 14 days of isolation, the patient was discharged. Conclusions: For children with newly diagnosed HB suspected of having COVID-19 during the pandemic period, clinicians must consider the prevention and control of COVID-19 while diagnosing and treating HB as soon as possible. Multidisciplinary management is beneficial for ensuring the development of a safe and efficient treatment plan.
