Advances in research on the relationship between tsRNAs and tumors
10.3969/j.issn.1000-8179.2020.02.197
- Author:
Xiaoxue HE
1
Author Information
1. Department of Gastroenterology, Yan An Hospital, Kunming Medical University
- Publication Type:Journal Article
- Keywords:
TiRNAs;
TRFs;
TsRNAs;
Tumors
- From:
Chinese Journal of Clinical Oncology
2020;47(2):85-88
- CountryChina
- Language:Chinese
-
Abstract:
Transfer RNA-derived small RNAs (tsRNAs) are an emerging class of non-coding single-stranded RNA that are derived from mature transfer RNA (tRNA) or tRNA precursors. They primarily consist of tRNA-derived RNA fragments (tRFs) and tRNA halves (tiRNAs). Studies have confirmed that tsRNAs are differentially expressed in a variety of tumors and involved in tumor processes including proliferation, invasion, and metastasis. Although the underlying mechanisms have not been fully elucidated, tsRNAs have the potential to be new biomarkers and therapeutic targets for tumors. This review provides an overview of the relationship between tsRNAs and common tumors to provide new ideas for the diagnosis, treatment, and prevention of tumors.
