18F-FDG PET/CT manifestations of Langerhans cell histiocytosis in adult spine
10.13929/j.1003-3289.201805081
- Author:
Yanyan ZHANG
1
Author Information
1. Department of Nuclear Medicine, Peking University Third Hospital
- Publication Type:Journal Article
- Keywords:
Adult;
Fluorodeoxyglucose F 18;
Langerhans cell histiocytosis;
Positron-emission tomography;
Spine
- From:
Chinese Journal of Medical Imaging Technology
2019;35(1):134-137
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe 18F-FDG PET/CT manifestations of Langerhans cell histiocytosis (LCH) of the adult spine. Methods 18F-FDG PET/CT imaging features of 9 adult patients with LCH of spine confirmed by pathology were retrospectively analyzed. The lesions number, location, density, margin and the maximum standardized uptake (SUVmax) were observed. Results Among 9 cases (18 lesions of spine), single lesion was found in 6 patients, while multiple lesions were found in 3 patients. Sixteen lesions displayed different degrees of osteolytic bone destruction, with sharp margins and were filled with soft tissue, 7 lesions showed rim osteosclerosis, while 3 lesions invaded canalis vertebralis. Another 2 lesions were found as shape shadow of slightly high density and no density abnormity, respectively. High 18F-FDG uptake was found in all 18 lesions, the mean SUVmax was 9.07±4.99. Conclusion 18F-FDG PET/CT manifestations of LCH of adult spine have some characteristics, which are helpful to the diagnosis of this disease.
