Comparative analysis of diffusion kurtosis imaging and intravoxel incoherent motion for evaluating histological classification and grading of cervical squamous cell carcinoma and cervical adenocarcinoma
10.13929/j.1003-3289.201803016
- Author:
Nan MENG
1
Author Information
1. Department of Magnetic Resonance, The First Affiliated Hospital of Xinxiang Medical University
- Publication Type:Journal Article
- Keywords:
Diffusion kurtosis imaging;
Intravoxel incoherent motion;
Magnetic resonance imaging;
Uterine cervical neoplasms
- From:
Chinese Journal of Medical Imaging Technology
2019;35(1):108-112
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the value of diffusion kurtosis imaging (DKI) and intravoxel incoherent motion (IVIM) in evaluation of histological classification and grading of cervical squamous cell carcinoma and cervical adenocarcinoma. Methods DKI and IVIM data of 60 patients with cervical cancer were retrospectively analyzed, and MK, MD, D, D* and f values were measured. The differences of the parameters between cervical squamous cell carcinoma group (n=38) and cervical adenocarcinoma group (n=22) were analyzed, as well as among different graded subgroups. The diagnostic efficiency of each parameter was evaluated with ROC curve, the correlations between the parameters and pathological grades were analyzed using Spearman method. Results MK of cervical squamous cell carcinoma group was higher than that of cervical adenocarcinoma group, while MD, D, D* and f were lower than those of cervical adenocarcinoma group (all P<0.05). In both groups, the differences of MK, MD and D were statistically significant among different subgroups (all P<0.05), while in cervical adenocarcinoma group, the differences of f were also statistically significant among different subgroups (all P<0.05). MK had the highest AUC in diagnosing cervical squamous cell carcinoma and adenocarcinoma.Except for D*, there was correlation between other parameters and pathological grade (all P<0.05). Conclusion Compared with IVIM, DKI can more effectively evaluate cervical squamous cell carcinoma and cervical adenocarcinoma and their pathological grading.
