Impact of different ROI and modulus of elasticity on shear wave elastography in diagnosis of benign and malignant cervical lymph nodes
10.13929/j.1003-3289.201807133
- VernacularTitle: 不同ROI和弹性模量值对剪切波弹性成像诊断颈部良恶性淋巴结效能的影响
- Author:
Zongyan DU
1
Author Information
1. Department of Ultrasound, The Affiliated Hospital of Qingdao University
- Publication Type:Journal Article
- Keywords:
Elastic modulus value;
Lymph nodes;
Region of interest;
Shear wave;
Ultrasonography
- From:
Chinese Journal of Medical Imaging Technology
2019;35(1):50-54
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the impact of different ROI and modulus of elasticity in shear wave elastography (SWE) for diagnosis of benign and malignant cervical lymph nodes. Methods Totally 143 enlarged cervical lymph nodes confirmed by puncture biopsy or surgical pathology were examined with routine ultrasound and SWE before operation. Three different ROI, including the small circular ROI (ROI-1) with diameter 2 mm, the maximum circle ROI (ROI-2) not exceeding the edge of the lymph node, and the manual delineation of the entire lymph node-marginal ROI (ROI-3) were used, all containing the hardest region of lymph nodes. The maximum elastic value (Emax), the mean elastic value (Emean) and the elastic standard deviation (SD) were measured and compared, respectively. ROC curve was constructed to obtain the AUC of each elasticity value for the diagnosis of benign and malignant lymph nodes in the neck. Results Emax, Emean and SD measured with 3 ROI in malignant lymph nodes were higher than those in benign lymph nodes (all P<0.001). There was no significant difference of Emax in benign lymph nodes, malignant lymph nodes nor total lymph nodes measured with 3 ROI (all P>0.05), but there was significant difference of Emean and SD (both P<0.001). The results of ROC curve showed that there was no significant difference among AUC of Emax measured with 3 ROI in diagnosis of benign and malignant lymph nodes (all P>0.05). AUC of Emean measured with ROI-1 was higher than those of ROI-2 and ROI-3 (both P<0.05), while SD was lower than those of ROI-2 and ROI-3 (both P<0.05), while there was no significant difference between the latter two (both P>0.05). Conclusion SWE could differentiate benign and malignant cervical lymph nodes, but its diagnostic efficacy varies with the choice of ROI and modulus of elasticity. When selecting a smaller ROI, it is recommended to use Emax and Emean, while Emax and SD are recommended when larger ROI is selected.
