Quantitative parameters of DWI and dynamic contrast-enhanced MRI in evaluating the depth of myometrial invasion of endometrial carcinoma
10.13929/j.1003-3289.201805139
- Author:
Jiming CHEN
1
Author Information
1. Medical Imaging Center, Yijishan Hospital of Wannan Medical College
- Publication Type:Journal Article
- Keywords:
Contrast media;
Endometrial neoplasms;
Magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging Technology
2019;35(2):226-230
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the value of DWI and dynamic contrast enhanced-MRI (DCE-MRI) quantitative parameters in evaluating the depth of myometrial invasion in patients with endometrial cancer. Methods Data of 45 patients with endometrioid adenocarcinoma confirmed by surgery and pathology were retrospectively analyzed. All patients underwent routine MRI, DWI and DCE-MRI 1-2 weeks before surgery. The patients were divided into no or superficial myometrial invasion group (n=25) and deep myometrial invasion group (n=20) according to the pathological results. The differences of ADC value and DCE-MRI quantitative parameters (Ktrans, Kep, Ve) were compared between the two groups. ROC curve was used to evaluate the diagnostic efficacy for depth of myometrial invasion in endometrial carcinoma. Results: Ktrans value of deep myometrial invasion group was higher than that of no or superficial myometrial invasion group (P=0.016). There was no significant difference in ADC value, Kep nor Ve between the two groups (all P>0.05). ROC curve analysis showed that the area under the curve of Ktrans was 0.735 (P=0.007). Taken Ktrans=0.355/min as the threshold, the sensitivity was 80.0%, and the specificity was 60.0% in diagnosis of depth of myometrial invasion in endometrial carcinoma. Conclusion: Ktrans may be useful for evaluating the depth of myometrial invasion of endometrial carcinoma.
