99Tcm-MDP SPECT/CT in diagnosis of pelvic insufficiency fracture of cervical cancer after radiotherapy
10.13929/j.1003-3289.201806029
- Author:
Rusen ZHANG
1
Author Information
1. Department of Nuclear Medicine, Cancer Center of Guangzhou Medical University
- Publication Type:Journal Article
- Keywords:
Facture, stress;
Pelvis;
Radionuclide imaging;
Tomography, emission-computed, single-photon;
Uterine cervical neoplasms
- From:
Chinese Journal of Medical Imaging Technology
2019;35(2):222-225
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the value of 99Tcm-MDP SPECT/CT in diagnosis of pelvic insufficiency fracture (PIF) of cervical cancer after radiotherapy. Methods Whole body scan (WBS) and 99Tcm-MDP SPECT/CT data of 37 suspected PIF patients with cervical cancer after radiotherapy were retrospectively analyzed. The diagnosis standard of PIF was based on radiologic investigation, clinical information and follow up for at least 12 months. The efficiency in diagnosis of PIF was compared between WBS and SPECT/CT. Results Among 37 patients (50 pelvic lesions ), 42 PIF lesions were diagnosed in 30 patients. The diagnostic sensitivity, specificity and accuracy of WBS diagnosis of PIF were 45.24% (19/42), 50.00% (4/8) and 46.00% (23/50), while of SPECT/CT diagnosis of PIF were 92.86% (39/42), 75.00% (6/8) and 90.00% (45/50), respectively. The diagnostic sensitivity and accuracy of SPECT/CT were significantly higher than those of WBS (χ2=22.28, 22.24, both P<0.01), and no significant difference of specificity was found between WBS and SPECT/CT (P=0.31). Conclusion: 99Tcm-MDP SPECT/CT can be used for diagnosis of PIF.