18F-FDG PET/CT and MR cholangiopancreatography multimodal imaging in diagnosis of malignant and benign obstructive jaundice
10.13929/j.1003-3289.201808031
- Author:
Caijun TENG
1
Author Information
1. Department of Nuclear Medicine, Liuzhou Worker's Hospital
- Publication Type:Journal Article
- Keywords:
Fludeoxyglucose F 18;
Jaundice, obstructive;
Magnetic resonance imaging;
Positron-emission tomography;
Tomography, X-ray computed
- From:
Chinese Journal of Medical Imaging Technology
2019;35(3):390-394
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the diagnostic value of 18F-FDG PET/CT combined with MR cholangiopancreatography (MRCP) multimodal imaging in diagnosis of malignant and benign obstructive jaundice. Methods Totally 57 biliary obstruction patients were enrolled and divided into malignant obstruction group (n=31) and benign obstruction group (n=26). The diagnostic efficacy of 18F-FDG PET/CT, MRCP and multimodal imaging of obstructive jaundice were analyzed and compared. Results In malignant obstruction group, moderate to severe biliary expansion accounted for 41.94% (13/31), while in the benign obstruction group, the rate was 3.85% (1/26), and the difference between the two groups was statistically significant (P=0.047). The maximum standard uptake value (SUVmax) of malignant obstruction group (10.54±6.69) was significantly higher than that of the benign obstruction group (3.78±1.68; P<0.001). The sensitivity of 18F-FDG PET/CT and MRCP in diagnosis of malignant obstructive jaundice was 90.32% (28/31) and 61.29% (19/31), the difference was statistically significant (P=0.046); the specificity was 84.62% (22/26) and 76.92% (20/26), the difference was not statistically significant (P=0.725); the accuracy was 87.72% (50/57) and 68.42% (39/57), and the difference was statistically significant (P=0.013). The sensitivity, specificity and accuracy of 18F-FDG PET/CT combined with MRCP multimodal imaging in diagnosis of malignant obstructive jaundice were 96.77% (30/31), 88.46% (23/26) and 92.98% (53/57), respectively, the differences were not statistically significant compared with PET/CT (all P>0.05), while compared with MRCP, the differences in sensitivity and accuracy were statistically significant (P=0.002, 0.002), the difference in specificity was not statistically significant (P=0.463). Compared with final results, the Kappa coefficients of multimodality imaging, 18F-FDG PET/CT and MRCP were 0.858, 0.752 and 0.375, respectively. Conclusion 18F-FDG PET/CT combined with MRCP multimodal imaging is helpful to improvement of the diagnostic accuracy of obstructive jaundice, which has important guiding significance for diagnosis and clinical treatment decision-making.
