Differential diagnosis of phyllodes tumor and fibroadenoma of breast using mammography and ultrasonography
10.13929/j.1003-3289.201809005
- Author:
Sina WANG
1
Author Information
1. Department of Radiology, Nanfang Hospital, Southern Medical University
- Publication Type:Journal Article
- Keywords:
Fibroadenoma;
Mammography;
Phyllodes tumor;
Ultrasonography
- From:
Chinese Journal of Medical Imaging Technology
2019;35(3):362-366
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To assess the clinical value of mammography and ultrasonography in diagnosis and differential diagnosis of breast phyllodes tumor and fibroadenoma. Methods Clinical, mammographic and sonographic findings were retrospectively analyzed and compared in 110 women with phyllodes tumor and 102 women with fibroadenoma confirmed by surgical pathology. Results The maximum diameter of phyllodes tumor ([4.61±3.35]cm) and fibroadenoma ([2.71±1.44]cm) were statistically different (P<0.001), and the difference of maximum diameter between benign and malignant phyllodes tumor was statistically significant (P=0.024). The mammogram parameters of tumor shape, margin, density and calcification were statistically different between phyllodes tumor and fibroadenoma (all P<0.05), and ultrasonography showed statistically significant differences in tumor shape, margin, internal cystic regions, posterior echo, blood flow classification (all P<0.05). Among the benign, borderline and malignant phyllodes tumors, the difference of cystic regions inside the tumor was statistically significant (P=0.006). Conclusion Combination of mammographic, sonographic and clinical findings can initially identify phyllodes tumor and fibroadenoma. When the tumor is large (>3.0 cm), lobulated, high density with internal cystic regions and abundant blood flow signal, phyllodes tumor should be considered.