Spatio-temporal image correlation and tissue Doppler imaging ultrasound in observation on fetal cardiac structure and function in pregnant women with gestational diabetes mellitus
10.13929/j.1003-3289.201810167
- Author:
Yuan WANG
1
Author Information
1. Department of Obstetrics and Gynecology, Peking University Civil Aviation School of Clinical Medicine
- Publication Type:Journal Article
- Keywords:
Diabetes;
Fetal heart;
gestational;
prenatal;
Spatio-temporal image correlation;
Ultrasonography
- From:
Chinese Journal of Medical Imaging Technology
2019;35(4):573-577
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the potential of spatio-temporal image correlation (STIC) and tissue Doppler imaging (TDI) in observation on fetal cardiac structure and function in pregnant women with gestational diabetes mellitus (GDM). Methods Totally 140 GDM pregnancies (40 in the insulin treatment group, 62 in the diet control group, 38 in the glycemic uncontrolled group) and 211 normal pregnancies (control group) were enrolled. STIC with M-mode display (STIC-M) was used to measure the thicknesses of fetal ventricular wall and interventricular septum at the end of diastole and systole. TDI ultrasound was used to measure fetal atrioventricular annular velocity in early diastole (Ea), during atrial contraction (Aa), and in systole (Sa), and to calculate the Ea/Aa ratios. The parameters were compared among the 4 groups. Results The overall differences of thickness of the left and right ventricular wall and interventricular septum at the end of diastole and systole were statistically significant among the 4 groups (all P<0.05), and those in all GDM pregnancy groups were higher than in control group (all P<0.05), whereas there was no significant difference among the 3 groups of GDM pregnancy (all P>0.05). The overall differences of mitral annular Ea/Aa among the 4 groups were statistically significant (P=0.002), and those in all GDM pregnancy groups were lower than in control group (all P<0.05), while there was no significant difference among the 3 groups of GDM pregnancies (all P>0.05). The differences in tricuspid annular Ea/Aa, mitral and tricuspid annular Sa were not statistically significant among 4 groups (all P>0.05). Conclusion The fetal ventricular wall and interventricular septum thicknesses are increased, cardiac diastolic function is decreased in GDM pregnancy independent of glycemic control condition. Combination of STIC-M and TDI has certain value to observe fetal cardiac structure and function in GDM pregnancy.
