Real-time shear wave elastography in differential diagnosis of benign and malignant peripheral lung masses
10.13929/j.1003-3289.201811157
- Author:
Lewen HUANG
1
Author Information
1. Department of Ultrasound, the First Affiliated Hospital of Nanchang University
- Publication Type:Journal Article
- Keywords:
Diagnosis, differential;
Lung neoplasms;
Shear wave elastography
- From:
Chinese Journal of Medical Imaging Technology
2019;35(5):687-690
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the value of shear wave elastography (SWE) in differential diagnosis of benign and malignant peripheral lung masses. Methods SWE examination was performed to measure the Young's modulus of 112 patients with peripheral pulmonary masses. The maximum value of Young's modulus (Emax) and the mean value of Young's modulus (Emean) were statistically analyzed between benign and malignant groups and among subgroups of different pathological types in malignant group. Taken pathological results as gold standards, ROC curve was drawn to evaluate the differential diagnostic efficacy of benign and malignant masses. Results: There were statistically significant differences of Emax and Emean between benign and malignant group (t=-2.78, -3.28, both P<0.01), while no significant difference of Emax and Emean was found among 3 subgroups of different pathological types in malignant group (both P>0.05). The cut-off value of Emax and Emean for differential diagnosis of benign and malignant masses was 10.35 kPa and 5.85 kPa, AUC was 0.74 (P=0.003) and 0.81 (P=0.001), respectively, while the sensitivity, specificity, positive predictive value and negative predictive value for diagnosis of malignant masses were 74.36%, 72.22%, 85.29%, 57.52%, and 81.58%, 80.78%, 89.57%, 67.67%, respectively. Conclusion: SWE technology can evaluate the elastic properties of peripheral lung masses and provide an important imaging diagnostic method for identifying benign and malignant peripheral lung masses.
