18F-FDG PET/CT dual-phase imaging in qualitative diagnosis of pulmonary occupying lesions
10.13929/j.1003-3289.201810029
- Author:
Lihong SHI
1
Author Information
1. Department of Nuclear Medicine, the First Affiliated Hospital of Zhengzhou University
- Publication Type:Journal Article
- Keywords:
Diagnosis, differential;
Fluorodeoxyglucose F 18;
Lung neoplasms;
Positron-emission tomography
- From:
Chinese Journal of Medical Imaging Technology
2019;35(5):682-685
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the value of 18F-FDG PET/CT dual-phase imaging in qualitative diagnosis of pulmonary occupying lesions. Methods Clinical and imaging data of 235 patients with pulmonary occupying lesions underwent 18F-FDG PET/CT dual-phase imaging were retrospectively analyzed. According to pathology results, the patients were divided into benign lesion group (n=80) and malignant lesion group (n=155). Maximal standardized uptake value (SUVmax) of pulmonary lesions in early and delayed imaging were compared between the two groups, and the change rate of SUVmax expressed as retention index (RI) were calculated. ROC curve was used to analyze the diagnostic efficacy of SUVmax in early and delayed imaging and RI for malignant pulmonary lesions. Results: The early and delayed SUVmax in malignant lesion group were both higher than those in benign lesion group, and the delayed SUVmax in both groups were higher than the early SUVmax (all P<0.001). RI in malignant lesion group was higher than that in benign lesion group (P<0.001). ROC curve analysis showed that AUC of early SUVmax, delayed SUVmax, RI and combined of them for diagnosis of pulmonary malignant lesions were 0.645, 0.697, 0.722 and 0.727, respectively (all P<0.05). Conclusion: 18F-FDG PET/CT dual-phase imaging can be used to qualitative diagnose pulmonary occupying lesions.
