Three-dimensional speckle tracking echocardiography in evaluation on left ventricular function in type 2 diabetes mellitus patients with non-alcoholic fatty liver disease
10.13929/j.1003-3289.201810042
- Author:
Yu DONG
1
Author Information
1. Department of Ultrasound, The Second Hospital of Dalian Medical University
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus, type 2;
Echocardiography, three-dimensional;
Fatty liver, non-alcoholic;
Ventricular function, left
- From:
Chinese Journal of Medical Imaging Technology
2019;35(6):837-842
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the feasibility of three-dimensional speckle tracking echocardiography (3D-STE) in evaluating left ventricular (LV) function in type 2 diabetes mellitus (T2DM) patients with non-alcoholic fatty liver disease (NAFLD). Methods: Totally 30 T2DM patients without NAFLD (group A), 32 T2DM patients with mild NAFLD (group B) and 35 T2DM patients with moderate to severe NAFLD (group C) underwent 3D-STE. Echocardiographic parameters were obtained, including conventional parameters of the ratio of transmitral peak early to late diastolic velocity (E/A), interventricular septum thickness diastolic (IVSTd), posterior wall thickness diastolic (PWTd), LV end-diastolic diameter (LVDd) and LV end-systolic diameter (LVDs), as well as LV function parameters including end-systolic left atrial volume (LAV), LV mass (LVM), LV end-diastolic volume (LVEDV), LV end-systolic volume (LVESV), LV mass index (LVMI) and LV ejection fraction (LVEF), also 3D-STE parameters including global longitudinal strain (GLS), global area strain (GAS), global radial strain (GRS) and global circumferential strain (GCS). The correlation of 3D-STE parameters and glycosylated hemoglobin (HbA1c), body mass index (BMI) were analyzed with Pearson linear correlation analysis. Results: There was no difference of E/A, IVSTd, PWTd, LVDd, LVDs, LVMI, LVEF, LVEDV nor LVESV among the 3 groups (all P>0.05), but patients in groups B and A had higher GCS, GRS, GLS and GAS than in group C (all P<0.05). The correlation analysis showed negative correlation between GLS, GRS, GCS, GAS and HbA1c (r=-0.540,-0.476,-0.489,-0.623, P=0.040, 0.032, 0.037, 0.020), while there was no obvious correlation between 3D-STE parameters and BMI (all P>0.05). Conclusion: 3D-STE can be used to assess LV function in T2DM patients with NAFLD.
