Quantitative acoustic radiation force impulse imaging in evaluation on elasticity of liver in patients with chronic heart failure
10.13929/j.1003-3289.201811100
- Author:
Jingwu YANG
1
Author Information
1. The Second School of Clinical Medicine, Southern Medical University
- Publication Type:Journal Article
- Keywords:
Elasticity imaging techniques;
Heart failure;
Liver;
Ultrasonography
- From:
Chinese Journal of Medical Imaging Technology
2019;35(7):1049-1052
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the value of quantitative acoustic radiation force impulse (ARFI) imaging in evaluation of liver elasticity in patients with chronic heart failure (HF). Methods: Totally 30 left HF patients (LHF group), 30 right HF patients (RHF group) and 30 healthy volunteers (control group) underwent routine ultrasound examination and biochemical examination, and then Young's modulus value of liver was detected using quantitative ARFI imaging. Correlations between Young's modulus value of liver and biochemical indexes, diameter of inferior vena cava, diameter of liver vein and oblique diameter of right lobe of liver were analyzed in patients with chronic HF. Results: Young's modulus value of liver in LHF group and RHF group were higher than that in control group (both P<0.05), and in RHF group was higher than in LHF group (P<0.05). Young's modulus value of liver in chronic HF patients positively correlated with brain natriuretic peptide, total bilirubin, gamma glutamyl transferase, alkaline phosphatase, diameter of inferior vena cava, diameter of left liver vein, diameter of middle hepatic vein and diameter of right liver vein (r=0.325, 0.382, 0.355, 0.379, 0.451, 0.445, 0.395, 0.645, all P<0.05), while no correlation was noticed between Young's modulus of liver and ejection fraction of left ventricle nor oblique diameter of right lobe of liver (all P>0.05). Conclusion: Quantitative ARFI imaging can be used to estimate the elasticity of liver in chronic HF patients. Liver elasticity is associated with the severity of heart failure.