Differences of structural asymmetry of cerebral cortex between easterner and westerner
10.13929/j.1003-3289.201903037
- VernacularTitle: 东西方人大脑皮层结构偏侧化的差异
- Author:
Sizhong ZHOU
1
Author Information
1. Beijing City Key Lab for Medical Physics and Engineering, Institute of Heavy Ion Physics, School of Physics, Center for MRI Research, Academy for Advanced Interdisciplinary Studies, Peking University
- Publication Type:Journal Article
- Keywords:
Asymmetry;
Cerebral cortex;
Culture difference;
Magnetic resonance imaging
- From:
Chinese Journal of Medical Imaging Technology
2019;35(8):1180-1184
- CountryChina
- Language:Chinese
-
Abstract:
Objective： To investigate the differences of structural asymmetry of cerebral cortex between Chinese Han people (eastern) and Caucasians (western) across different ages. Methods： Structural T1WI from the young group and old group (each group n=30) of both Han people and Caucasians. Brainnetome Atlas was used to parcellate brain cortices. The lateralization index of cortical area, cortical thickness and mean curve in each brain region were computed, and the differences were compared between Han people and Caucasians. Results： Significantly asymmetric results appeared in cortical area, cortical thickness and mean curve in young group and old group of both Han people and Caucasians. The number of brain regions with significant asymmetry in cortical surface area was larger than that with asymmetry in cortical thickness and mean curve. The number of brain regions with significant asymmetry was larger in young groups than in old groups, but there was no significant difference in lateralization index between young groups and old groups. Significant lateral differences distinguishing Han people and Caucasians centered around BA45, BA13, BA9 and BA14 (FDR corrected, all P<0.05). Conclusion： Significant lateral asymmetry in Han people and Caucasians were mainly observed in regions functionally responsible for cognitive processes of language, memory and face discrimination.
