Comparison on clinical and CT features of adenoid cystic carcinoma and mucoepidermoid carcinoma in central airway
10.13929/j.1003-3289.201901196
- Author:
Weijie LUO
1
Author Information
1. Department of Radiology, The First Affiliated Hospital of Guangzhou Medical University
- Publication Type:Journal Article
- Keywords:
adenoid cystic;
Carcinoma;
Carcinoma;
mucoepidermoid;
Salivary gland neoplasms;
Tomography;
X-ray computed
- From:
Chinese Journal of Medical Imaging Technology
2019;35(9):1352-1355
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To compare CT features and clinical manifestations of adenoid cystic carcinoma (ACC) and mucoepidermoid carcinoma (MEC) in the central airway. Methods: A total of 76 patients with central airway salivary gland tumor proved by surgery or biopsy (45 patients with ACC and 31 patients with MEC) were analyzed retrospectively. All patients underwent chest CT, among them 38 patients with ACC and 29 patients with MEC underwent contrast enhanced CT. CT features of the tumor, including growth location, maximum diameter, growth pattern, enhancement, obstructive pneumonia, atelectasis, lymphadenopathy and pleural effusion were evaluated. Results: Patients with MEC were younger than those with ACC (P<0.01). There was no significant difference in incidence rate of cough, expectoration, fever, hemoptysis, difficulty breathing nor chest pain between two groups (all P >0.05). Compared with MEC, ACC was more likely to occur in trachea, behaved as infiltrative growth, less enhancement and lower incidence of obstructive inflammation(all P<0.05). However, there was no significant difference in tumor maximum diameter and the incidence of obstructive atelectasis, lymph node enlargement nor pleural effusion between MEC and ACC patients (all P>0.05). Conclusion: The age of onset of central airway salivary gland tumor is younger. ACC is more likely to occur in the trachea, most of them show invasive growth, while enhancement CT shows mild to moderate enhancement. MEC is more likely to occur in lobar and segmental bronchi, most of them show expansive growth and significantly enhancement on CT. The incidence of obstructive inflammation is higher in MEC patients than in ACC patients.
