DWI based on monoexponential and biexponential models in differential diagnosis of benign and malignant lung lesions: Meta-analysis
10.13929/j.1003-3289.201902049
- Author:
Junhao HUANG
1
Author Information
1. Department of Radiology, Yongchuan Hospital of Chongqing Medical University
- Publication Type:Journal Article
- Keywords:
Biexponential models;
Diffusion weighted imaging;
Intravoxel incoherent motion;
Lung neoplasms;
Meta-analysis;
Monoexponential models
- From:
Chinese Journal of Medical Imaging Technology
2019;35(9):1346-1351
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the diagnostic efficacy of DWI based on monoexponential and biexponential models in differential diagnosis of benign and malignant lung lesions. Methods: Studies related to diagnosis of benign and malignant lung lesions by DWI based on monoexponential and biexponential models were retrieved from Embase, Pubmed, Cochrane Library, CNKI, Wanfang Med Online and VIP databases which were performed up to December, 2018. The studies that meet the inclusion criteria were evaluated with quality assessment of diagnostic accuracy studies. Meta-Disc version 1.4 and STATA 15.0 software were used for statistics analysis. Results: Totally 10 studies (5 English, 5 Chinese), including a total of 695 lesions in 672 patients were enrolled. The sensitivity of ADC value and D value in differential diagnosis of benign and malignant lung lesions was 0.78 (95%CI [0.73, 0.83]), 0.90 (95%CI [0.87, 0.93]), specificity was 0.71 (95%CI [0.64, 0.78]), 0.64 (95%CI [0.57, 0.70]), the diagnostic odds ratio was 12.59 (95%CI [4.93, 32.11]), 19.58 (95%CI [7.06, 54.29]), and the AUC of summary ROC curve was 0.848 9, 0.885 1, respectively. Conclusion: ADC value and D value both have good diagnostic efficacy in distinguishing benign and malignant lung lesions, and the diagnostic efficacy of D value is better than ADC value.
