MSCT features of hepatic metastases of nonhypervascular pancreatic neuroendocrine tumor and pancreatic ductal adenocarcinoma
10.13929/j.1003-3289.201903022
- Author:
Jianwei SU
1
Author Information
1. Department of Radiology, Daxing Teaching Hospital of Capital University of Medical Sciences
- Publication Type:Journal Article
- Keywords:
Adenocarcinoma;
Hepatic metastases;
Neuroendocrine tumors;
Pancreatic neoplasms;
Tomography, X-ray computed
- From:
Chinese Journal of Medical Imaging Technology
2019;35(11):1678-1682
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore MSCT features of hepatic metastases of nonhypervascular pancreatic neuroendocrine tumor(PNET) and pancreatic ductal adenocarcinoma (PDAC), and its value for differential diagnosis. Methods: A total of 21 patients with nonhypervascular PNET and 56 patients with PDAC associated with hepatic metastases were analyzed retrospectively. The CT features of hepatic metastases including tumor number, distribution, size, fusion of lesions, abnormal hepatic perfusion and the CT enhancement degree were observed and analyzed. Results: There was no significant difference of the tumor number, distribution and lesion fusion of hepatic metastases between nonhypervascular PNET and PDAC (all P>0.05). There was significant difference of the maximum diameter of hepatic metastases between nonhypervascular PNET and PDAC (P=0.03). The incidence of abnormal hepatic perfusion of PDAC was higher than that of nonhypervascular PNET (67.86% vs 28.57%,P<0.01). In arterial phase, portal phase and equilibrium phase, the enhancement index of hepatic metastases of nonhypervascular PNET were all higher than that of PDAC(P<0.01). Logistic regression analysis showed that only the enhancement index in arterial phase was an independent factor for differentiating hepatic metastases between nonhypervascular PNET and PDAC, with AUC of 0.97. Conclusion: The imaging features of hepatic metastases on MSCT is helpful for differentiating diagnosis of nonhypervascular PNET and PDAC.