Three-dimensional echocardiography combined with myocardial contrast echocardiography for assessment of myocardial dysfunction in patients with type 2 diabetes mellitus
10.13929/j.1003-3289.201906024
- Author:
Jiahui ZENG
1
Author Information
1. Department of Medical Ultrasound, The First Affiliated Hospital, Institute of Diagnostic and Interventional Ultrasound, Sun Yat-sen University
- Publication Type:Journal Article
- Keywords:
Diabetes complications;
Echocardiography, three-dimensional;
Myocardial perfusion imaging;
Ultrasound contrast
- From:
Chinese Journal of Medical Imaging Technology
2019;35(11):1611-1615
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the value of real-time three-dimensional echocardiography (RT-3DE) combined with myocardial contrast echocardiography (MCE) in evaluating myocardial dysfunction in type 2 diabetes mellitus (T2DM) patients. Methods: Totally 58 T2DM patients were divided into group (T2DM isolated ) and group Ⅱ (T2DM associated with microvascular complications, each n=29). Group C included 32 normal individuals. The standard deviation (Tmsv16-SD, Tmsv12-SD, Tmsv6-SD) and the maximum time difference (Tmsv16-Dif, Tmsv12-Dif, Tmsv6-Dif) of the time to the minimum systolic volume of left ventricle were measured with RT-3DE. MCE was performed to obtain perfusion measurement of each segment of ventricular wall, including the acoustic intensity (A), microvascular flow velocity (β) and A•β. Results: There were statistically significant differences in all synchronize measurements except Tmsv6-Dif between group Ⅱ and group C (all P<0.05). Tmsv12-Dif, Tmsv12-SD, Tmsv12-Dif% and Tmsv12-SD% of group prolonged comparing with group C (all P<0.05). All the parameters of A, β and A•β showed a gradually decreasing trend in group C, group and group Ⅱ, while those in group Ⅱ were lower than group C (all P<0.05). The parameters of β and A•β in group Ⅱ were lower than those in group (both P<0.05). Compared with group C, the values of β and A•β in group decreased (both P<0.05). There was no significant difference of the same measurement in segments among three groups (all P>0.05). Conclusion: Left ventricular desynchrony can be observed in T2DM patients with or without microvascular complications. Myocardial perfusion reduce in T2DM patients presenting as diffuse damage, which aggravated with microvascular complications in other organs.
