MRI volume quantitative analysis in evaluation on therapeutic effect of wrist rheumatoid arthritis
10.13929/j.issn.1003-3289.2020.01.034
- Author:
Lixiang REN
1
Author Information
1. Department of MRI, The First People's Hospital of Yunnan Province
- Publication Type:Journal Article
- Keywords:
Arthritis, rheumatoid;
Magnetic resonance imaging;
Quantitative analysis
- From:
Chinese Journal of Medical Imaging Technology
2020;36(1):120-124
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the application value of MRI quantitative analysis in evaluation on therapeutic effect of rheumatoid arthritis (RA) of the wrist. Methods: Totally 30 patients with RA after regular treatment for 1 year were enrolled. The wrist joint was scanned before and after treatment, and the volume of synovitis and bone marrow edema before and after treatment were measured by using the quantitative analysis software. The erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) and disease activity score of 28 (DAS28) were also obtained. Changes of synovitis, bone marrow edema, CRP, ESR and DAS28 were analyzed before and after treatment, correlation analysis was performed on the changes of synovitis and bone marrow edema with changes of CRP, ESR and DAS28. Results: After treatment, the volume of synovitis, the range of bone marrow edema, CRP, ESR and DAS28 of the patients reduced significantly (all P<0.05). Synovitis was strongly correlated with changes in bone marrow edema (r=0.61, P<0.01). Changes in synovitis and bone marrow edema were not significantly correlated with those of ESR and CRP (all P>0.05), while changes in synovitis and bone marrow edema were moderately correlated with changes of DAS28 (r=0.50, 0.56, P=0.01,<0.01). Conclusion: MRI quantitative analysis can be used as accurate and Objective: quantitative indices for monitoring and evaluating therapeutic effect of RA.
