18F-FDG PET/CT parameters combined with clinical features in predicting prognosis of patients with early cervical cancer
10.13929/j.issn.1003-3289.2020.01.030
- Author:
Chen XU
1
Author Information
1. Department of Radiology, Shengjing Hospital of China Medical University
- Publication Type:Journal Article
- Keywords:
Fluorodeoxyglucose F18;
Lymph nodes;
Prognosis;
Uterine cervical neoplasms
- From:
Chinese Journal of Medical Imaging Technology
2020;36(1):106-110
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the prognostic value of 18F-FDG PET/CT parameters combined with clinical features in predicting prognosis of early cervical cancer patients after surgical operation. Methods: A total of 70 cervical cancer patients who underwent 18F-FDG PET/CT before operation were collected and retrospectively analyzed. Differences of metabolic parameters were compared between relapsed patients (relapse group) and non-recurrent ones (non-recurrent group). The predictive value of 18F-FDG PET/CT parameters combined with clinical features for prognosis were analyzed. Results: The mean follow-up time was (53.86±15.74) months, and recurrence of cervical cancer occurred in 11 patients (11/70, 15.71%). The peak standard uptake value (SUVpeak) was the only 18F-FDG PET/CT parameter predicting recurrence (AUC=0.672, P=0.03). Multivariate proportional hazards model (Cox) showed that lymph node metastatic status and SUVpeak were the most important predictors. Conclusion: SUVpeak and lymph node metastatic status are main indicators for evaluating prognosis of patients with early cervical cancer after surgical operation.
