Impact of menstrual status on the apparent diffusion coefficient of different pathological types of cervical cancer
10.13929/j.issn.1003-3289.2020.04.022
- VernacularTitle: 月经状态对不同病理类型宫颈癌表观弥散系数值的影响
- Author:
Yue DONG
1
Author Information
1. Department ofMedical Imaging, Cancer Hospital of China Medical University
- Publication Type:Journal Article
- Keywords:
Magnetic resonance imaging;
Menstruation;
Uterine cervical neoplasms
- From:
Chinese Journal of Medical Imaging Technology
2020;36(4):569-573
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the impact of menstrual status on the apparent diffusion coefficient (ADC) of cervical squamous cell carcinoma and adenocarcinoma. Methods: MRI and DWI data of 352 patients with pathologically confirmed cervical cancer were retrospectively analyzed, including 317 cases of cervical squamous cell carcinoma and 35 with cervical adenocarcinoma. Among 352 patients, 177 were premenopausal and 175 were menopausal. The maximum ADC (ADCmax), minimum ADC (ADCmin) and mean ADC (ADCmean) values of the lesions were measured and recorded at the maximum level of cervical carcinoma on ADC images. ADC values were compared between cervical squamous cell carcinoma and adenocarcinoma, also between postmenopausal and pre-menopausal patients, further between cervical squamous cell carcinoma and adenocarcinoma in postmenopausal and pre-menopausal patients. Results: The ADCmin and ADCmean values of cervical squamous cell carcinoma were lower than those of adenocarcinoma (t=-2.05, -2.28, both P<0.05). For pre-menopausal patients, the ADCmean and ADCmin values of cervical squamous cell carcinoma were lower than those of adenocarcinoma (t=-4.40, -5.40, both P<0.05), while for menopausal patients, the ADCmean, ADCmin and ADCmax of cervical squamous cell carcinoma were similar to those of adenocarcinoma (t=0.82, 1.57, 0.45, all P>0.05). The ADCmin, ADCmean and ADCmax values of premenopausal patients with cervical squamous cell carcinoma or adenocarcinoma were higher than those of postmenopausal patients (t=-3.96, -2.53, -2.78 and t=-3.71, -1.15, -5.01, all P<0.05). Conclusion: ADC values of cervical cancers are different with different pathologic types, which affected by the menstrual statue of patients. ADC value of adenocarcinoma is higher than that of squamous cell carcinoma in pre-menopausal patients, while is similar in post-menopausal patients. ADC values of cervical cancers in pre-menopausal patients are higher than those in post-menopausal patients.
