Longitudinal layer-specific strain imaging in evaluation of early changes of left ventricular systolic function and synchrony in patients with systemic lupus erythematosus
10.13929/j.issn.1003-3289.2020.05.012
- VernacularTitle: 纵向分层应变评价早期系统性红斑狼疮左心室收缩功能及同步性改变
- Author:
Fangfang WANG
1
Author Information
1. Department of Ultrasound, the First Affiliated Hospital of Zhengzhou University
- Publication Type:Journal Article
- Keywords:
Echocardiography;
Lupus erythematosus, systemic;
Ventricular function, left
- From:
Chinese Journal of Medical Imaging Technology
2020;36(5):696-701
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the early changes of left ventricular systolic function and synchrony in systemic lupus erythematosus (SLE) patients with longitudinal layer-specific strain imaging. Methods: Forty-two SLE patients (SLE group) and 30 healthy subjects (control group) were collected. Two-dimensional gray-scale moving images of three long axial sections of the left ventricular apex were stored, and the parameters of the longitudinal strain (LS) and peak strain dispersion (PSD) were obtained. The differences of these parameters were compared between groups. According to SLEDAI-2000 scoring system, the patients were divided into inactive phase (SLE-) subgroup and active phase (SLE+) subgroup, and the differences of related parameters were further analyzed. Results: Compared with control group, except apical segment, the LS of global and segmental three-layer myocardium decreased in SLE group (all P<0.05). Among SLE group, LS of global and segmental three-layer myocardium decreased in SLE+ subgroup (all P<0.05), while only the endocardial LS of the global, basal of left ventricle were found lower in SLE- subgroup than in control group (both P<0.05). PSD were higher in SLE group and both 2 subgroups of SLE than in control group (all P<0.05). There was no significant difference of LS of left ventricular myocardium nor PSD between 2 subgroups of SLE (all P>0.05). Conclusion: Longitudinal layer-specific strain imaging can be used to sensitively evaluate the subclinical left ventricular myocardial changes in SLE patients.
