Arrival time parametric imaging of contrast enhanced ultrasound for differential diagnosis of gallbladder lesions
10.13929/j.issn.1003-3289.2020.06.014
- VernacularTitle: 超声造影到达时间参数成像鉴别诊断胆囊病变
- Author:
Hewen TANG
1
Author Information
1. Key laboratory of Carcinogenesis and Translational Research [Ministry of Education/Beijing], Department of Ultrasound, Peking University Cancer Hospital & Institute
- Publication Type:Journal Article
- Keywords:
Arrival time parametric image;
Gallbladder diseases;
Gallbladder neoplasms;
Ultrasonography
- From:
Chinese Journal of Medical Imaging Technology
2020;36(6):863-867
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the value of arrival time parametric imaging (ATPI) of contrast-enhanced ultrasonography (CEUS) for differential diagnosis of gallbladder lesions. Methods: Data of 25 patients with gallbladder carcinoma and 22 with benign gallbladder lesions who received CEUS and cholecystectomy were reviewed. ATPI system was used to analyze CEUS imaging. The artery patterns of the lesions on ATPI in artery phase were evaluated. Then quantitative parameters, including arrival time of gallbladder lesions, arrival time of surrounding liver as well as the time difference (△T) were analyzed. Results: The artery patterns were different between benign and malignant gallbladder lesions in artery phase (P<0.001). Malignant lesions often presented as branched and irregular artery pattern, while benign lesions tended to present as scattered dot and linear artery pattern, but the arrival time of them were not statistical different (P>0.05). However, △T (the arrival time difference of lesions and the surrounding liver) of benign (-0.21±1.37)s and malignant (-2.69±1.37)s lesions were statistically significant (P<0.001).Taken -1.05 s as the cut off value of △T, the sensitivity, specificity, positive predictive value, negative predictive and value accuracy in differentiating gallbladder carcinoma from benign lesions was 81.80%, 92.00%, 85.20%, 90.00% and 87.20%, respectively. Conclusion: Artery patterns and parameters of ATPI of CEUS are helpful to differential diagnosis of benign and malignant gallbladder lesions.
