Correlation between standard uptake value of lumbar vertebrae in 99Tcm-MDP bone imaging and bone mineral density
10.13929/j.issn.1003-3289.2020.07.032
- VernacularTitle: 99Tcm-MDP骨显像腰椎标准摄取值与骨密度的相关性
- Author:
Fengwen YU
1
Author Information
1. Department of Nuclear Medicine, The First People's Hospital of Foshan
- Publication Type:Journal Article
- Keywords:
Bone density;
Lumbar vertebrae;
Osteoporosis;
Tomography, emission-computed, single-photon
- From:
Chinese Journal of Medical Imaging Technology
2020;36(7):1070-1074
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the differences of standard uptake value (SUV) of lumbar vertebrae in 99Tcm-methylene diphosphonate (99Tcm-MDP) bone imaging in patients with different bone mineral density (BMD), and to analyze the correlation with BMD. Methods: Data of 62 patients who underwent 99Tcm-MDP bone imaging, lumbar SPECT/CT imaging and dual energy X-ray BMD examination were retrospectively analyzed. According to BMD, the patients were divided into normal bone mass group (n=18), bone mass reduction group (n=24) and osteoporosis group (n=20). The differences of lumbar mean SUV (SUVmean), maximum SUV (SUVmax), BMD and so on were calculated and compared among 3 groups, and the correlations of them and lumbar mean CT value and patient's, age, weight and height were analyzed. Results: SUVmax and SUVmean of lumbar vertebra were 7.39±1.84 and 4.90±1.27, respectively, both positively correlated with BMD (r=0.64, 0.63, all P<0.01). Statistical differences of lumbar SUVmax, SUVmean, BMD and mean CT values were found among 3 groups (F=24.09, 30.50, 94.85, 30.24, all P<0.01). SUVmax, SUVmean and BMD of lumbar vertebra were all negatively correlated with aging (r=-0.33, -0.44, -0.43, all P<0.05) but positively correlated with body weight (r=0.42, 0.30, 0.35) and mean CT value (r=0.56, 0.59, 0.73, all P<0.05), while not correlated with body height (all P>0.05). Lumbar SUVmax, SUVmean, BMD and mean CT values of bone mass reduction group were significantly lower than those of normal bone group (all P<0.01), of osteoporosis group were significantly lower than those of normal bone group and bone mass reduction group (all P<0.01). Conclusion: Lumbar SUV of 99Tcm-MDP bone imaging can be used to evaluate osteoporosis and therapeutic effect. SUVmax and SUVmean of lumbar vertebra are positively correlated with BMD. Lumbar SUVmax and SUVmean significantly decreased in osteoporosis patients.
