SPECT/CT pulmonary perfusion imaging in evaluating efficacy of pulmonary balloon dilatation for treatment of chronic thromboembolic pulmonary hypertension
10.13929/j.issn.1003-3289.2020.07.019
- VernacularTitle: SPECT/CT肺灌注显像评价肺动脉球囊扩张成形术治疗慢性血栓栓塞性肺动脉高压效果
- Author:
Xinhua DING
1
Author Information
1. Department of Nuclear Medicine, Gansu Provincial Hospital
- Publication Type:Journal Article
- Keywords:
Angioplasty, balloon;
Hypertension, pulmonary;
Positron-emission tomography;
Pulmonary embolism;
Tomography, X-ray computed
- From:
Chinese Journal of Medical Imaging Technology
2020;36(7):1022-1026
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the efficacy of SPECT/CT pulmonary perfusion imaging for evaluation on therapeutic effect of balloon dilatation (BPA) for chronic thromboembolic pulmonary hypertension (CTEPH). Methods: A total of 18 patients with CTEPH underwent SPECT/CT pulmonary perfusion imaging before and 1-3 months after BPA. Perfusion defect and perfusion improvement were observed before and after BPA taken catheter pulmonary angiography as standards. Results: The sensitivity, specificity, accuracy, positive predictive value (PPV) and negative predictive value (NPV) of SPECT/CT pulmonary perfusion imaging in detecting pulmonary perfusion defect was 90.42%(302/334), 99.05%(418/422), 95.24%(720/756), 98.69%(302/306), 92.89%(418/450), respectively before BPA, while perfusion improvement after BPA was 77.78%(56/72), 80.00%(24/30), 78.43%(80/102), 90.32%(56/62) and 60.00%(24/40), respectively. Conclusion: SPECT/CT pulmonary perfusion imaging has good clinical value in evaluating pulmonary segment perfusion and improvement in patients with CTEPH after BPA.
