Study on chemical constituents of Kochia scoparia
- Author:
Xiang-Hong LU
1
Author Information
1. Lishui People's Hospital
- Publication Type:Journal Article
- Keywords:
5, 7, 4'-trihydroxy-6, 3'-dimethoxyflavone;
5, 7, 4'-trihydroxy-6-methoxy-flavone;
Flavonoids;
Kochia scoparia;
Triterpenoids
- From:
Chinese Pharmaceutical Journal
2012;47(5):338-342
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the constituents in the fruits of Kochia scoparia. METHODS: Various column chromatographic techniques were used to isolate the constituents, and their structures were identified by ESI-MS, NMR spectral data and by comparison spectra with literature data. RESULTS: Sixteen compounds were isolated and elucidated as stearic acid (1), β-sitosterol (2), oleanolic acid (3), daucosterol(4), 5, 7, 4'-trihydroxy-6, 3'-dimethoxyflavone (5), 5, 7, 4'-trihydroxy-6-methoxyflavone (6), isorhamnetin (7), quercetin (8), isorhamnetin -3-O-β-D-glucopyranoside(9), rutin(10), oleanolic acid-3-O-β-D-glucuronopyranoside(11), oleanolic acid-3-O-β-D-xylopyranosyl(1 → 3)-β-D-(6-O-methyl)-glucuronopyranoside(12), oleanolic acid-3-O-β-D-xylopyranosyl(1 → 3)-β-D-glucuronopyranoside(13), 3-O-β-D-glucuronopyranosyl-oleanolic acid-28-O-β-D-glucopyranoside(14), 3-O-β-D-xylopyranosyl(1 → 3)-β-D-glucuronopyranosyl-oleanolic acid-28-O-β-D-glucopyranoside(15), 3-O-{[β-D-β-D-glucopyranosyl(1 → 2)]-[β-D-xylopyrano-syl(1 →3)]-)-β-D-glucuronopyranosyl oleanolic acid-28-O-β-D-glucopyranoside(16). CONCLUSION: Compounds 5-10 were isolated from Kochia scoparia. for the first time. Copyright 2012 by the Chinese Pharmaceutical Association.