Study on microwave digestion of vacant gelatin capsules
- Author:
Ke-Ran FENG
1
Author Information
1. National Institutes for Food and Drug Control
- Publication Type:Journal Article
- Keywords:
Hydrogen peroxide;
Microwave digestion;
Vacant Gelatin Capsules
- From:
Chinese Pharmaceutical Journal
2012;47(11):919-922
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To assure the safety and improve the efficiency of microwave digestion of vacant gelatin capsules. METHODS: Different digestion conditions were investigated by using microwave digestion system with temperature and pressure sensors to determine the optimal experimental method. RESULTS: Using high proportion of hydrogen peroxide in pre-digestion could moderate the increase of pressure in microwave digestion process and at the same time shorten time and improve the digestion efficiency. CONCLUSION: This method, which improves the experimental safety and applicability, is an effective way to solute the long pre-digestion time of the method of Ch. P(2010) and the burst with ordinary digestion tanks.
