Study on quality standards of Huoxue Zhitong Preparations
- Author:
Li-Xing NIE
1
Author Information
1. National Institutes for Food and Drug Control
- Publication Type:Journal Article
- Keywords:
Angelicae Sinensis Radix;
Borneolum Syntheticum;
Ferulic acid;
HPLC;
Huoxue Zhitong Capsules;
Huoxue Zhitong Powders;
Olibanum;
TLC identification
- From:
Chinese Pharmaceutical Journal
2012;47(12):989-992
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To improve the quality standards of Huoxue Zhitong Powders and Huoxue Zhitong Capsules. METHODS: Angelicae Sinensis Radix, Olibanum and Borneolum Syntheticum were identified simultaneously by TLC method. Ferulic acid was detected by HPLC method. RESULTS: Clear spots were obtained with good separation in TLC identification. For the HPLC determination of ferulic acid, the calibration curve was linear in the range of 0.2-200 μg · mL-1, the limit of detection was 0.054 μg · mL-1 and recoveries were between 95%-105%. CONCLUSION: The proposed method is specific, accurate, simple and applicable for better control of Huoxue Zhitong Preparations' quality.
