Chemical constituents from Origanum vulgare
- Author:
Yu-Shan GUO
1
Author Information
1. Department of Phytochemistry
- Publication Type:Journal Article
- Keywords:
(+)-(R)-butyl rosmarinate;
1, 2, 4-benzenetriol;
6, 7, 4'-trihydroxyflavone;
Flavone;
Lamiaceae;
Methyl 3-(3', 4'-di-hydroxyphenyl) lactate;
Origanum vulgare;
Phenols
- From:
Chinese Pharmaceutical Journal
2012;47(14):1109-1113
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To investigate the chemical constituents of Origanum vulgare L. METHODS: The chemical constituents were isolated by silica gel, ODS, Sephadex LH-20, as well as RP-HPLC column chromatographies. Their structures were elucidated based on their physicochemical properties and spectral data. RESULTS: Thirteen compounds were isolated from O. vulgare. Their structures were identified as 4-(O-β-D-glucopyranosyl)-hydroxy-7-(3', 4'-dihydroxy-benzoyl)-benzyl alcohol(1), 5, 7, 4'-trihy-droxy-8-C-p-hydroxybenzylflavone(2), 6, 7, 4'-trihydroxyflavone(3), 1, 2, 4-benzenetriol(4), methyl 3-(3', 4'-dihydroxyphenyl) lactate (5), (+)-(R)-butyl rosmarinate (6), didymin (7), apigenin (8), apigenin 7-O-β-D-glucoside (9), luteolin (10), ferulaic acid (11), caffeic acid (12) and β-sitosterol(13) Respectively. CONCLUSION: Compounds 1~7 were isolated from O. vulgare for the first time. Copyright 2012 by the Chinese Pharmaceutical Association.
