Chemical constituents of Axinella sp. from the South China Sea
- Author:
Wen-Jie XU
1
Author Information
1. Shenzhen Salubris Pharmaceuticals CO., LTD
- Publication Type:Journal Article
- Keywords:
2'-deoxyuridine;
Axinella sp.;
Marine sponge;
Spongothymidine;
Spongouridine;
Structure elucidation
- From:
Chinese Pharmaceutical Journal
2012;47(22):1799-1802
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the chemical constituents of Axinella sp. from the South China Sea. METHODS: The compounds were isolated and purified by silica gel, Sephadex LH-20, and semi-preparative reverse-phase HPLC(C18). Their structures were identified by their spectral data. RESULTS: Ten compounds were isolated from Axinella sp. and their structures were identified as cyclo-(Val-Pro) (1), cyclo-(Tyr-Pro) (2), cyclo-(Phe-Pro) (3), cyclo-(Leu-Pro) (4), cyclo-(Ile-Pro) (5), 2'-deoxyinosine (6), 2'-deoxyadenosine(7), spongothymidine (8), spongouridine (9) and 2'-deoxyuridine (10). CONCLUSION: All the compounds were isolated from Callyspongia sp. for the first time.
