Study on Swertia mussotii Franch. by HPLC fingerprinting method combined with chemical pattern recognition approaches
- Author:
Cheng-Wang TIAN
1
Author Information
- Publication Type:Journal Article
- Keywords: Fingerprint; HPLC-MS; Principal component analysis; Swertia mussotii Franch.
- From: Chinese Pharmaceutical Journal 2013;48(18):1545-1549
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To study the quality control method of Swertia mussotii Franch. METHODS: A high performance liquid chromatographic method was developed to establish the fingerprint of Swertia mussotii Franch. Nineteen samples from various batches were analyzed, furthermore, PCA were used to differentiate and evaluate the whole fingerprints. Some characteristic peaks were i-dentified preliminarily with HPLC-MS method. RESULTS: Eleven peaks were identified by MS. Swertiamarin and swertianolin were the key components for quality control. CONCLUSION: The method provides an academic reference for controlling the quality of Swertia mussotii Franch.
