Chiral resolution of ondansetron hydrochloride enantiomers by high performance liquid chromatography
- Author:
Yan-Jie YIN
1
Author Information
- Publication Type:Journal Article
- Keywords: Chiral stationary phase; Enantiomers; HPLC; Impurity; Ondansetron hydrochloride; Resolution
- From: Chinese Pharmaceutical Journal 2014;49(22):2027-2030
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To establish a fast and efficient HPLC method for the chiral separation of ondansetron hydrochloride and determination of the enantiomic impurity of (-)ondansetron(R)hydrochloride.