Simultaneous determination of cyclosprine a, tacrolimus, sirolimus, mycophenolic acid, and prednisolone by UPLC-MS/MS
- Author:
Wen-Qian CHEN
1
Author Information
- Publication Type:Journal Article
- Keywords: Immunosuppressant; Prednisolone; Renal transplantation; TDM; UPLC-MS/MS
- From: Chinese Pharmaceutical Journal 2014;49(20):1845-1849
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To establish an UPLC-MS / MS method for simultaneous determination of a variety of drugs used for im¬munosuppressive therapy in the whole blood of renal transplant patients and to use this method for blood concentration monitoring in therapeutic: drug monitoring.