Replacing solubilizer with lipid microspheres eliminates the severe adverse reaction of vitamin K1 injection
- Author:
Yan-Ni MI
1
Author Information
- Publication Type:Journal Article
- Keywords: Anaphylactoid reaction; Anaphylaxis; Beagle dog; Injection; Lipid microsphere; RBL-2H3 cell; Vitamin K1
- From: Chinese Pharmaceutical Journal 2014;49(20):1832-1835
- CountryChina
- Language:Chinese
- Abstract: OBJECTIVE: To investigate whether substituting the solubilizer with lipid microspheres in vitamin K1 injection can eliminate the anaphylactoid reaction.