Sulforaphane and its derivative BSFN induced apoptosis in SH-SY5Y cells by activating the PI3K/Akt signaling pathway

Author: Jie REN ¹
Author Information

1. School of Pharmceutical Engineering and Life Science, Changzhou University
Publication Type:Journal Article
Keywords: 1-[(4-isothiocyanatobutylsulfinyl) methyl] benzene; Apoptosis; PI3K/Akt; SH-SY5Y cells; Sulforaphane
From: Chinese Pharmaceutical Journal 2014;49(20):1813-1819
CountryChina
Language:Chinese
Abstract: OBJECTIVE: To study the effect of sulforaphane (SFN) and its derivative 1-((4-isothiocyanatobutylsulfinyl) methyl) benzene(BSFN), a PI3K/Akt inhibitor, on the proliferation and apoptosis of SH-SY5Y cells and the possible action mechanism.