Evaluation of in vitro affinity of brucine to P-glycoprotein

Author: Dan-Hua XU ¹
Author Information

1. The Fourth Affiliated Hospital of Zhengjiang University School of Medicine
Publication Type:Journal Article
Keywords: Blood brain barrier; Brucine; In vitro affinity; P-glycoprotein
From: Chinese Pharmaceutical Journal 2014;49(18):1631-1636
CountryChina
Language:Chinese
Abstract: OBJECTIVE: To evaluate the affinity of brucine, a central stimulant, with P-gp in vitro, and predict its potential as a P-gp substrate in vivo.