Relations between results of chromosomal analysis and fetal abnormalities determined by ultrasound
- Author:
An Van To
;
Tuan Anh Le
- Publication Type:Journal Article
- Keywords:
chromosomal analysis;
fetal abnormalities
- MeSH:
chromosomal analysis;
fetal abnormalities
- From:Journal of Medical and Pharmaceutical Information
2005;0(12):28-30
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Background: Abnormal chromosome may be abnormal in number or structure of chromosomes related to normal chromosomes or sex chromosomes. One sign of abnormal chromosomes that we can observe during pregnancy is the abnormal ultrasound images. Objectives: To discover the relations between the chromosomal abnormalities and some fetal abnormalities determined by ultrasound. Subjects and method: A prospective descriptive study combined with a retrospective study on 250 pregnant women with fetal abnormalities from Aug 2006 to Aug 2008. Results: Among 250 pregnant women with fetal abnormalities determined by ultrasound taken amniocentesis, rate of late amniocentesis (over 20 weeks) was the highest (50.8%), while rate of ideal amniocentesis (16-20 weeks) only accounted for 29.6%. Abnormal chromosomal rate of multiple abnormalities of fetus statistically significant were higher than that of mono abnormal of fetus (46.8% vs. 18.5%/ p<0.0l). Conclusion: Abnormal phenotype determined by ultrasound; rate of chromosomal disorder was 27.2%.
